Abstract

The COVID-19 pandemic brought about large increases in mental distress. The uptake of COVID-19 vaccines is expected to significantly reduce health risks, improve economic and social outcomes, with potential benefits to mental health. To examine short-term changes in mental distress following the receipt of the first dose of the COVID-19 vaccine. Participants included 8,003 adults from the address-based sampled, nationally representative Understanding America Study (UAS), surveyed at regular intervals between March 10, 2020, and March 31, 2021 who completed at least two waves of the survey. Respondents answered questions about COVID-19 vaccine status and self-reported mental distress as measured with the four-item Patient Health Questionnaire (PHQ-4). Fixed-effects regression models were used to identify the change in PHQ-4 scores and categorical indicators of mental distress resulting from the application of the first dose of the COVID-19 vaccine. People who were vaccinated between December 2020 and March 2021 reported decreased mental distress levels in the surveys conducted after receiving the first dose. The fixed-effects estimates show an average effect of receiving the vaccine equivalent to 4% of the standard deviation of PHQ-4 scores (p-value<0.01), a reduction in 1 percentage point (4% reduction from the baseline level) in the probability of being at least mildly depressed, and of 0.7 percentage points (15% reduction from the baseline level) in the probability of being severely depressed (p-value = 0.06). Getting the first dose of COVID-19 resulted in significant improvements in mental health, beyond improvements already achieved since mental distress peaked in the spring of 2020.

Highlights

  • The COVID-19 pandemic has affected several aspects of people’s lives, including their employment and finances, health risks and opportunities to socialize, all of which can affect mental health

  • Fixedeffects regression models were used to identify the change in PHQ-4 scores and categorical indicators of mental distress resulting from the application of the first dose of the COVID-19 vaccine

  • People who were vaccinated between December 2020 and March 2021 reported decreased mental distress levels in the surveys conducted after receiving the first dose

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Summary

Introduction

The COVID-19 pandemic has affected several aspects of people’s lives, including their employment and finances, health risks and opportunities to socialize, all of which can affect mental health. In the US, mental health distress rose sharply early in the pandemic and recovered partially. Mental health distress rose to a peak in April, but improved since and by August had returned to a level comparable to that of early March [3]. Several factors contributed to the rise in mental health problems in the pandemic. Some studies have suggested that economic concerns were the most strongly associated with worsening mental health, while concerns about their own health and social distance were correlated though less strongly [4]. The uptake of COVID-19 vaccines is expected to significantly reduce health risks, improve economic and social outcomes, with potential benefits to mental health. To examine short-term changes in mental distress following the receipt of the first dose of the COVID-19 vaccine

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