Abstract
(1) Background: Older people with COVID-19 infection report worse clinical outcomes. There is a paucity of local data and this study aimed to describe the clinical progression of older people admitted to a university hospital in Malaysia with COVID-19 infection. (2) Methods: Older people (≥60 years) admitted with COVID-19 infection confirmed with RT-PCR from 27 February 2020–25 May 2020 were included in this study. Data on patient characteristics, hospital treatment, and inpatient outcomes were collected via hospital-held electronic medical records. Analysis was done to describe the cohort and identify factors associated with inpatient mortality. (3) Results: 26 participants were included (mean age 76.2 years, female 57.7%). All had at least one comorbid condition and half were frail. About 19.2% had non-respiratory (atypical) symptoms; 23.1% had a severe disease that required intensive care unit monitoring; 46.2% were given COVID-19 targeted therapy. Inpatient mortality and overall complication rates were 23.1% and 42.3%, respectively. Delirium on presentation and lower Ct-value were associated with mortality. (4) Conclusions: Older people with COVID-19 infection have severe infection and poor hospital outcomes. Vigilant hospital care is necessary to address their multimorbidity and frailty, along with appropriate treatment for their infection.
Highlights
Worse clinical outcomes were observed among those aged 65 years and above withCOVID-19 infection
This study aimed to describe the characteristics, presentation, treatment, and hospital-specific healthcare outcomes of the older person admitted for COVID-19 infection to a university hospital in Malaysia
This is a retrospective study of Malaysian nationality aged 60 years old and above, diagnosed with COVID-19 infection, and treated in University Malaya Medical Centre (UMMC) from 25 February 2020 till 27 May 2020
Summary
Worse clinical outcomes were observed among those aged 65 years and above withCOVID-19 infection. Worse clinical outcomes were observed among those aged 65 years and above with. The case fatality rate was reported to be as high as 14.8–20.2% in those aged 80 years and above [1,2]. In Malaysia, there are currently 100,318 reported cases, with 446 deaths, for a total case fatality rate of 0.45% [3,4]. 64% of these reported deaths involved an older person [3,4]. Older people were at least 2.5 times more likely to require intensive care or die, as compared to their younger counterparts [5]. Hospital treatment, prolonged bed rest, and isolation precautions might increase the risk of other adverse outcomes, such as deconditioning, delirium, hospital-acquired infection, and pressure sore
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