Abstract

Cover Illustration: Triple confocal immunofluorescence image of a primary astrocyte (green; GFAP) which has engulfed Abeta-containing synaptoneurosomes (red; Abeta42) derived from APP mice. Lysosomes (blue; Lamp1) surround the internalized synaptic elements but there is no overlap between both compartments indicating an inefficient degradation capacity. (See Sanchez-Mico, MV et al, https://doi.org/10.1002/glia.23943.)

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