Abstract
Low-frequency electrical stimulation at sites in the frontal cortex of the rat will suppress running in an activity wheel, but will have no effect on general activity measured in a stabilimeter. This confirms a prediction made from the effects of frontal lesions on these two kinds of activity. No evidence of abnormality in the EEG was observed following frontal stimulation. Stimulation in the frontal cortex probably influences the same inhibitory processes that are modified by frontal lesions. Further results indicate that the differential effects of frontal stimulation on running and general activity may be partly due to differences in response effort required.
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