Corrigendum

Abstract

Journal of AnatomyVolume 233, Issue 2 p. 274-274 CorrigendumFree Access Corrigendum This article corrects the following: Sealed osteons in animals and humans: low prevalence and lack of relationship with age John G. Skedros, Tanner R. Henrie, Madison S. Doutré, Roy D. Bloebaum, Volume 232Issue 5Journal of Anatomy pages: 824-835 First Published online: February 19, 2018 First published: 11 June 2018 https://doi.org/10.1111/joa.12834AboutSectionsPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Skedros JG, Henrie TR, Doutré MS, and Bloebaum RD (2018) Sealed osteons in animals and humans: low prevalence and lack of relationship with age. Journal of Anatomy, 232 (5), 824–835. https://doi.org/10.1111/joa.12786. In Skedros et al. 2018, the authors wish to make minor text corrections and add an important reference Kornblum & Kelly (1964) to the section titled ‘Closing cone hypothesis’. The original text is as follow: Closing cone hypothesis The smaller size of sealed + partially sealed osteons in all of our samples leads us to hypothesize that they represent the closing cone region of the Haversian system. The basic multicellular unit (BMU) is a temporary structure for bone remodeling, made up of osteoclasts and osteoblasts (Parfitt, 1994). During bone remodeling, the BMU propagates, with a cutting cone (osteoclasts) leading the BMU and a closing cone (osteoblasts) in its wake. We hypothesize that the majority of sealed + partially sealed osteons likely represent the closing cone region that is known to occur in some regions of secondary osteons (Cohen and Harris, 1958, Cooper et al. 2006, Maggiano et al. 2016) and, therefore, are not a pathological or otherwise ischemia-related infilling of the Haversian canal with bone tissue. The revised text should read: Closing cone hypothesis The smaller size of sealed + partially sealed osteons in all of our samples leads us to hypothesize that they represent the closing region of the Haversian system. The basic multicellular unit (BMU) is a temporary structure for bone remodeling, made up of osteoclasts and osteoblasts (Parfitt, 1994). During bone remodeling, the BMU propagates, with a cutting cone (osteoclasts) leading the BMU and a closing cone (osteoblasts) in its wake. We hypothesize that the majority of sealed + partially sealed osteons likely represent the closing region that is known to occur in some secondary osteons (Cohen and Harris, 1958, Cooper et al. 2006, Maggiano et al. 2016) and, therefore, are not a pathological or otherwise ischemia-related infilling of the Haversian canal with bone tissue. Kornblum & Kelly (1964) also reached the same conclusion in their microscopic study of transverse sections of the tibial shafts of 12 non-ischemic limbs compared to 21 ischemic limbs that ultimately had amputation. References Kornblum SS, Kelly PJ (1964) The lacunae and haversian canals in tibial cortical bone from ischemic and non-ischemic limbs. A comparative microradiographic study. J Bone Joint Surg Am 46, 797– 810. Skedros JG, Henrie TR, Doutré MS, et al. (2018) Sealed osteons in animals and humans: low prevalence and lack of relationship with age. J Anat 232, 824– 835. Volume233, Issue2August 2018Pages 274-274 ReferencesRelatedInformation