Abstract
Thirty-three patients with new-onset type 1 diabetes from Zhongshan Hospital, Fudan University were recruited from 2013 to 2014. Relevant clinical data were collected for the statistical analysis. Among the 33 patients with type 1 diabetes, there were 7 with fulminant type 1 diabetes(FT1DM), 12 acute onset type 1 diabetes(AT1DM), and 14 with slowly progressive type 1 diabetes(SPIDDM). The fasting and stimulated C-peptide levels were significantly lower while glycated albumin(GA)/HbA1C and mean amplitude of glucose excursions(MAGE)levels were significantly higher in FT1DM group compared with other two groups(all P<0.05). Pearson correlation analysis in all patients with type 1 diabetes revealed that GA/HbA1C was correlated with fasting C-peptide, MAGE, and difference of the peak blood glucose to the lowest blood glucose(ΔBG)levels(all P<0.05). Stepwise multivariate analysis showed that GA/HbA1C was independently correlated with MAGE and ΔBG(P<0.05). Logistic regression model indicated that GA, HbA1C, and GA/HbA1C were independently correlated with FT1DM. (Chin J Endocrinol Metab, 2017, 33: 326-329) Key words: Diabetes mellitus, type 1; Fulminant type 1 diabetes; Glycated albumin; HbA1C
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