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Abstract
This study investigated the correlation between anti-HCV antibodies in saliva and HCV RNA in saliva and salivary glands of patients with chronic hepatitis C. Methods: A total of 131 non-stimulated and 49 stimulated saliva samples were tested for anti-HCV antibodies. Results were compared with HCV RNA detection in saliva and salivary glands. Statistical analysis was done. Results: Antibodies were detected in 26.1% of the saliva samples. In 23.5% of these, HCV RNA was detected. Of the 73.9% of saliva samples with undetectable antibodies, 36.8% were positive for HCV RNA. In 26.6% of the patients with salivary gland samples there were detectible antibodies in the saliva. Of these, 11.8% had HCV RNA in the salivary gland. From the 73.4% cases negative for salivary antibodies, 21.3% were positive for HCV RNA in the salivary gland. Conclusion: There was no correlation between anti-HCV antibodies in saliva and HCV RNA in saliva and salivary glands. Support: FAPEMIG.
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