Abstract

BackgroundThis prospective study was conducted between January 2015 and June 2018 and included 50 patients (mean age of 52.12 ± 2.0 years), all presented with acute pancreatitis and admitted to the ICU 1–3 days after the onset. All patients underwent contrast-enhanced CT, and images are evaluated by 2 independent radiologists for the modified CTSI parameters and retroperitoneal extension parameters to detect the severity of pancreatitis. The aim of this study is to compare the results of the modified CT severity index and retroperitoneal interfascial extension CT grading system in the grading of the severity of acute pancreatitis and compare both grading systems to the clinical course of the disease and its complications.ResultsBoth grading systems show a statistical significant correlation in terms of the length of hospital stay, the need for interventions, and the development of organ failure.ConclusionIn conclusion, a good correlation was observed between the modified CTSI and retroperitoneal extension grading systems in grading the severity of acute pancreatitis. We think that we can apply Ishikawa et al. grading system as a prognostic indicator if there is a contraindication to contrast administration.

Highlights

  • This prospective study was conducted between January 2015 and June 2018 and included 50 patients, all presented with acute pancreatitis and admitted to the ICU 1–3 days after the onset

  • Patients This prospective study was conducted between January 2015 and June 2018 in the tertiary center and included 50 patients, (40 males and 10 females) with a mean age of 52.12 ± 2.0 years, all presented with acute pancreatitis and admitted to the intensive care unit 1–3 days after the onset of the symptoms

  • This study included 50 patients, all of them presented with acute pancreatitis and admitted to the intensive care unit; the causes of pancreatitis were due to gallstones in 29, alcohol abuse in 3 patients, post ERCP inflammation in 9, and miscellaneous or unknown etiology in 9 patients

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Summary

Introduction

This prospective study was conducted between January 2015 and June 2018 and included 50 patients (mean age of 52.12 ± 2.0 years), all presented with acute pancreatitis and admitted to the ICU 1–3 days after the onset. The aim of this study is to compare the results of the modified CT severity index and retroperitoneal interfascial extension CT grading system in the grading of the severity of acute pancreatitis and compare both grading systems to the clinical course of the disease and its complications. Acute pancreatitis is a frequently appreciated severe disease and can be associated with the spreading of the inflammatory process and leakage of the pancreatic fluid [1]. The retroperitoneal cavity is divided into three parts: the anterior pararenal, posterior pararenal, and perirenal spaces. They are demarcated by the prerenal fascia, lateroconal fascia, and posterior renal fascia [5]

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