Correlation between global indices of short‐wavelength automated perimetry and GDx VCC parameters

Abstract

Abstract Purpose: To correlate the main indices of short‐wavelength automated perimetry (SWAP) with the peripapillary retinal nerve fiber layer thickness measured with the scanning laser polarimeter GDx VCC (Laser Diagnostic Technologies, Inc., San Diego, CA) in different diagnostic groups. Methods: 400 eyes were divided into 56 control eyes, 211 ocular hypertensive subjects, 67 glaucoma suspects and 66 glaucomatous patients, depending on intraocular pressure, optic nerve head morphologhy and standard automated perimetry (Humphrey 24‐2 SITA standard). Only one eye was randomly chosen for the study. SWAPs were performed with a Humphrey perimeter and the 24‐2 full threshold algorithm. Pearson correlations between SWAP indices (mean deviation ‐MD‐ and pattern standard deviation –PSD‐) and GDx VCC parameters (Nerve fiber indicator –NFI‐, TSNIT average, superior average, inferior average and TSNIT standard deviation) were calculated for each group of subjects. Results: Mild significant (p<0.05) correlations were observed between SWAP indices and most GDx parameters in the glaucoma suspect and the glaucomatous groups. Few GDx parameters showed mild correlations with the indices of SWAP in the normal group, but no significant correlations were found in the ocular hypertensive group. The TSNIT standard deviation exhibited the strongest correlation with the MD in the glaucoma group (0.33). Conclusions: Laser polarimetry parameters showed mild correlations with SWAP defects in glaucoma subjects.