Correlation between blood pressure variability and different types of stroke

Abstract

Objective To explore the relationship between blood pressure variability and different types of stroke. Methods One hundred and twenty-five ischemic stroke subjects, 78 hemorrhagic stroke patients and 66 non-stroke individuals, collected in our hospital from January 1, 2013 to December 31, 2015, were enrolled according to the inclusion and exclusion criteria. All indicators of blood pressure variability were calculated from 24 h ambulatory blood pressure, including nighttime blood pressure fall (BPF), morning surge in blood pressure (MBPS), standard deviation (SD), weighted SD (wSD), and coefficient of variation (CV). Results As compared with non-stroke subjects, ischemic and hemorrhagic stroke individuals had significantly increased systolic MBPS (P<0.05), and the systolic MBPS of ischemic stroke group was significantly lower than those of hemorrhagic stroke group (P<0.05). CV, wSD and BPF of systolic blood pressure (SBP) in the ischemic and hemorrhagic groups were significantly higher than those in the non-stroke subjects (P<0.05); CV and SBPF of diastolic blood pressure in hemorrhagic group were significantly different as compared those in the non-stroke subjects (P<0.05). The factors which were significantly associated with ischemic stroke in Logistic regression, included high-density lipoprotein, nighttime SBP, wSD of SBP, CV of SBP, while smoking, nighttime SBP, wSD of SBP, MBPS, and CV of SBP were observed as important influence factors for hemorrhagic stoke patients. Conclusion Whether ischemic stroke, or hemorrhagic stroke are associated with short-term blood pressure variability. Key words: Stroke; Blood pressure variability; Morning surge; Standard deviation; Nighttime blood pressure fall