Abstract

PurposeTo determine the distributions and relation of central corneal thickness (CCT) and intraocular pressure (IOP) by NT-530P in Chinese juveniles, and the effect of gender, age, height, weight and refractive errors on the CTT and IOP.MethodsCCT and IOP of 982 eyes in 514 juveniles aged from 7 to 18 years were measured with NT-530P. Multi-linear regression and ANOVA analysis were used to analyze the relation of CCT and IOP, and the effect of gender, age, height, weight, refractive condition on CCT and IOP respectively.ResultsThe mean CCT and IOP were 554.19±35.46 µm and 15.31±2.57 mmHg. There were significant correlations between the CCT and IOP values. Linear regression analysis revealed a positive correlation between CCT and IOP (r = 0.44, P<0.05). Linear regression equation: IOP = −2.35+0.032CCT, which means the IOP will increase 0.32 mm Hg for every 10-µm increase in CCT. The mean of Corrected IOP (CIOP) was 15.32±2.38 mmHg and had no relation with CCT. There was a negative correlation between refraction degree and CCT (P<0.05), but no correlation between refraction degree and IOP. Multi-linear regression model revealed that the height, weight, age and gender have no effect on the distribution of CCT and IOP respectively.ConclusionsThere is a 0.32 mmHg increase in IOP for every 10-µm increase in CCT. The height, weight, age and gender has no effect on the distribution of CCT and IOP. CCT will become thinner with myopia diopters increases in juveniles. The measurement of CCT is helpful in evaluating the actual IOP correctly.

Highlights

  • With the rapid development of refractive surgery, central corneal thickness (CCT) has become an important parameter for choosing surgery modality and assessing prognosis

  • This study aims to evaluate the relation of CCT and intraocular pressure (IOP) in Chinese school children aged from 7 to 18 years, and elaborate the effect of gender, age, height, weight and refractive errors on the relation of CCT and IOP

  • NT-530P automatically measures CCT in each subject using the principle of the Scheimpflug camera system following the same principle as the Pentacam [6,7] and measures IOP like a conventional noncontact tonometer which uses a puff of air to flatten the cornea

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Summary

Introduction

With the rapid development of refractive surgery, central corneal thickness (CCT) has become an important parameter for choosing surgery modality and assessing prognosis. NT-530P automatically measures CCT in each subject using the principle of the Scheimpflug camera system following the same principle as the Pentacam [6,7] and measures IOP like a conventional noncontact tonometer which uses a puff of air to flatten the cornea. It provides IOP and CIOP which is corrected according to CCT at the same time.NT-530P offers a non-invasive CCT and IOP measurement in a single unit and reduces a patient’s discomfort with continuously measurements.

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