Abstract

Correction: MRI Evidence for Altered Venous Drainage and Intracranial Compliance in Mild Traumatic Brain Injury

Highlights

  • Traumatic brain injury (TBI) affects over 1.4 million individuals annually in the United States alone [1]

  • The majority of TBI are classified as mild traumatic brain injury defined as a blunt head trauma resulting in transient confusion, disorientation, impaired or loss of consciousness lasting 30 minutes or less in combination with a number of unspecific neurological and cognitive symptoms [1,2,3]

  • All subjects were questioned in detail regarding general and neurological health and completed a detailed standardized questionnaire based on the criteria for mild traumatic brain injury (mTBI) of the Centers for Disease Control (CDC)

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Summary

Introduction

Traumatic brain injury (TBI) affects over 1.4 million individuals annually in the United States alone [1]. The majority of TBI are classified as mild traumatic brain injury (mTBI) defined as a blunt head trauma resulting in transient confusion, disorientation, impaired or loss of consciousness lasting 30 minutes or less in combination with a number of unspecific neurological and cognitive symptoms [1,2,3]. Advanced MR based imaging and spectroscopy techniques, such as functional MRI (fMRI) [6,7], diffusion tensor imaging (DTI) [8,9,10], and MR spectroscopy [11] have shown to be more sensitive in detecting alterations in the brain following mTBI. MRS demonstrated widespread cellular metabolic dysfunction including a decrease of N-acetyl aspartate and an increase in total choline. These changes correlated with neuropsychological parameters after mTBI [11]

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