Abstract
The conjugate addition of organomagnesium reagents to α, β-ethylenic esters is performed in THF, at room temperature (30 min to 1.5 h), in the presence of CuCl (3%) and Me 3SiCl (1.2 eq.). Good yields of 1,4-addition products are obtained according to this very simple procedure.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
