Abstract

An efficient, one-pot, three-component synthesis of some novel heteroaryl aminoindandione derivatives using ninhydrin, various heteroaryl amines, and barbituric/2-thiobarbituric acids catalyzed by p-toluenesulfonic acid as organocatalyst has been achieved within a short period of time. The present methodology offers several advantages including operational simplicity, clean reaction, high yield, short reaction times, high atom economy, easy workup procedure, and simple purification of products by nonchromatographic methods.

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