Abstract
We introduce the contraction graph as a novel graphical representation of RNA secondary structure. A contraction operation - defined along base pairs, single stranded regions, and tertiary interactions - allows for representing RNA secondary structure at different levels of detail. Directionality of the graph and flow conservation of the contraction operation allow for explicit representation of the 5' and 3' ends of the molecule. Furthermore, existing representations such as tree and dual graphs are specific instances in this framework. We anticipate that this unified representation will facilitate automated motif finding and functional classification based on direct searches and comparisons of RNA secondary structure topology.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
