Contemporary Use Of Topical Decongestants: An Indian Perspective

Abstract

Background: Allergic rhinitis and sinusitis are commonly encountered in primary practice, and nasal congestion is a common symptom experienced by these patients. Thus, it is important to address nasal congestion when treating these conditions. Despite the availability of several treatment options, therapy is impacted by adverse effects and patient dissatisfaction. We conducted a survey to evaluate the prescribing practices of physicians treating allergic rhinitis and sinusitis, with a focus on the formulation of topical xylometazoline with moisturizers (hypromellose and sorbitol). Methods: We surveyed the prescribing practices of 545 Indian ear, nose and throat (ENT) physicians for rhinitis and sinusitis to understand the place of the formulation containing xylometazoline and moisturizer (sorbitol, hypromellose) in clinical practice. Towards this, physicians provided their response to a 10-item questionnaire covering prescribing practice and patient satisfaction. Results: Overall, 91% of doctors reported that a decongestant along with a moisturizer would be beneficial to patients with nasal congestion due to allergic rhinitis and sinusitis, and a majority of doctors (89.5%) preferred prescribing xylometazoline with sorbitol and hypromellose. A majority of doctors reported high patient satisfaction with this formulation. Additionally, 78.35% of doctors reported high ratings for the reduction of nasal dryness. Conclusion: The overall satisfaction of doctors and patients is high, indicating that this formulation is an ideal choice for achieving relief from nasal congestion due to AR and sinusitis.