Abstract
Abstract 1,2,3,4,4a,9,9a,10-Octahydroanthracene and tetralin derivatives with known absolute configurations were synthesized to estimate the contribution of a methyl substituent at the third sphere to the Cotton effect induced in the benzenoid transitions. The contributions were estimated from the CD spectra obtained based on the conformation of the skeleton deduced by Force Field Theory and the assumption that the contributions are additive. A large contribution was observed for the 1-quasiequatorial-methyl group in the 1Lb benzenoid transition and for the 2-axial-methyl group in the 1La benzenoid transition. The sign agreed well with the rule proposed by Snatzke except for the contribution of ring B in the 1La benzenoid transition.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
