Abstract
2-Aminothiazoles and 2-aminobenzothiazoles react with β-chlorovinyl ketones in the presence of acid in two directions to form isomeric thiazolo[3,2-a]pyrimidinium compounds. In the absence of acid, the aminothiazole is alkylated only at the cyclic nitrogen atom without closing of the pyrimidine ring. The PMR spectra were used to establish the structures of the reaction products and to determine the ratios of isomers formed.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
