Abstract
Summary1. The condensation product of BAL and oxophenarsine hydrochloride (BAL-OXO) was studied. Its toxicity in mice and chemotherapeutic activity in T. equiperdum is reported, in comparison with similar data, for oxophenarsine hydrochloride.2. The acute toxicity of the thioarsenite, BAL-OXO is approximately 1/4 that of the arsenoxide (oxophenarsine hydrochloride) from which it was prepared.3. The BAL-OXO has less therapeutic advantage, i.e., lower LD50/CD50, in mouse trypanosomiasis than oxophenarsine hydrochloride itself.
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