Abstract
As a result of APA labelling with 99mTc reduced by SnCl2 at pH 1.9 about 90% of 99mTc-APA complex was obtained. Experiments in vivo were carried out on 10 Swiss mice who had Ehrlich tumor inplanted. After 8 days the 99mTc-APA complex was administered i. p. – The ADF ratio tumor blood was 2,5. Renoscintigraphy showed that the decline of renal activity, in the stage when excretion prevailed (phase III), was slow and of cumulative nature. Simple synthesis, labelling and low toxity of APA are the factors that advocate further experiments in searching its utility in diagnostics.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Isotopenpraxis Isotopes in Environmental and Health Studies
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
