Abstract
Ecdisten waste-recycling processes were studied for rational use of the rhizomes with roots of Rhaponticum carthamoides. Separation of flavonoids from ecdysteroids over polyamide at 25:1 and 30:1 ratios of sorbent layer height to column diameter and a 1:8 ratio of material to sorbent were proposed. It was found that the crude product should be recrystallized from 70% EtOH at a product:solvent ratio of 1:30 and the aqueous EtOH solution of total flavonoids should be condensed to one third of the initial volume followed by storage in a crystallizer for at least 8 h to obtain substance containing at least 95% total flavonoids from the crude product. A complex processing technology for rhizomes with roots of R. carthamoides that could produce substance of the adaptogen ecdisten, substance of a hypoazotemic drug based on total flavonoids, and lipid concentrate for use in cosmetology was developed. A spectrophotometric method for quantitative determination at 353 ± 2 nm of total flavonoids recalculated as luteolin was proposed.
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