Abstract

A study has been made of the complexing behavior of potato and arrowroot starch with a number of pharmaceutical compounds. By means of the solubility method of analysis, it has been found that the starches form complexes in solution with benzoic acid, salicylic acid, p-hydroxybenzoic acid, m-hydroxybenzoic acid, p-aminobenzoic acid, methyl p-hydroxybenzoate, ethyl p-hydroxybenzoate, ethyl p-aminobenzoate, and propyl p-hydroxybenzoate. No evidence of complex formation was detected between the starches and caffeine. It is postulated that attractive forces and inclusion formation are responsible for the interaction observed. A study has been made of the complexing behavior of potato and arrowroot starch with a number of pharmaceutical compounds. By means of the solubility method of analysis, it has been found that the starches form complexes in solution with benzoic acid, salicylic acid, p-hydroxybenzoic acid, m-hydroxybenzoic acid, p-aminobenzoic acid, methyl p-hydroxybenzoate, ethyl p-hydroxybenzoate, ethyl p-aminobenzoate, and propyl p-hydroxybenzoate. No evidence of complex formation was detected between the starches and caffeine. It is postulated that attractive forces and inclusion formation are responsible for the interaction observed.

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