Abstract
Ectopic testis predisposes to a high risk of germ cell tumor development. Treatment of advanced testicular germ cell tumor developing in an uncorrected abdominal testis is based on primary chemotherapy followed by removal of the testis along with residual masses. However, persistence of viable tumor particularly in the testis is always noted since testis penetration of chemotherapeutic agents is reduced. We report a case of complete pathological remission of a patient with advanced non-seminomatous germ cell tumor in intra-abdominal testis by primary chemotherapy alone, with a review of the literature.
Highlights
Germ cell tumors of the testis (GCT) have their highest incidence in young adults
The risk of developing testicular cancer is affected by the location of the undescended testis, in a way that inguinal testes are four times less likely to become cancerous compared with intra-abdominal testes [3]
We reported here a case of advanced GCT in a neglected cryptorchid testis in a 40-year-old man where primary cisplatin-based chemotherapy resulted in a pathological and sustained complete remission confirmed by secondary surgery and follow-up
Summary
Germ cell tumors of the testis (GCT) have their highest incidence in young adults. The risk of developing testicular cancer is affected by the location of the undescended testis, in a way that inguinal testes are four times less likely to become cancerous compared with intra-abdominal testes [3]. How to cite this paper: Sarkis, P., et al (2014) Complete Remission by Primary Chemotherapy of Advanced Non-Seminomatous Germ Cell Tumor in an Intra-abdominal Testis. Treatment of advanced tumors in these testes is based on primary chemotherapy followed by surgery of all residual masses. We reported here a case of advanced GCT in a neglected cryptorchid testis in a 40-year-old man where primary cisplatin-based chemotherapy resulted in a pathological and sustained complete remission confirmed by secondary surgery and follow-up
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