Abstract

In scanning the literature on complement fixation for tuberculosis, one is astonished at the number of substances used as antigen for this test and the great diversity of results obtained, some authors asserting only a 50 per cent. efficiency for the test, and others that the test even outclasses the Wassermann reaction, with 95 or more per cent. positive reactions in active cases. Some are so bold in their contention as to hold a positive complement fixation test as an indication of the presence or absence of tuberculosis which requires treatment against all other findings. There seems to be no uniformity in the findings and contentions of any two observers, owing probably to the facts that each observer is working with his own new antigen, and that only a few go far enough into the work to compare a number of different antigens. Elizabeth Fraser<sup>1</sup>stands out preeminently as

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