Abstract
The purpose of this study was to compare and evaluate the event of VTE (Venous Thromboembolism Event) after total artificial joint replacement between two groups diagnosed with either musculoskeletal tumors or osteoarthritis (OA) of the knee. From 2004 to 2014, a total of 1,402 patients (308 in tumor group, 1,094 in OA group) were involved in this study. The rate of asymptomatic DVT (Deep vein thrombosis) was significantly higher in tumor group when compared with OA group. Though both the incidence of symptomatic DVT and PE (Pulmonary embolism) were slightly higher in tumor group, no significant difference was detected. Tumor patients suffered an almost equal risk of VTE compared with OA patients except a higher rate of asymptomatic DVT after total artificial joint replacement. For patients with tumor, no significant association was observed between any potential risk factor and DVT.
Highlights
Postoperative venous thromboembolism, which encompasses deep vein thrombosis and pulmonary embolism, has been recognized as a potentially life-threatening complication[1]
Orthopedic surgery especially that involving lower limbs has always been regarded as a risk factor for the development of venous thromboembolism[3]
We retrospectively reviewed the clinical records from January 2004 to January 2014 and selected patients who were scheduled for artificial knee joint replacement surgery with confirmed diagnosis of osteoarthritis or musculoskeletal tumors
Summary
Postoperative venous thromboembolism, which encompasses deep vein thrombosis and pulmonary embolism, has been recognized as a potentially life-threatening complication[1]. In England, more than 25,000 people die of venous thromboembolism each year for various kinds of surgeries[2]. Orthopedic surgery especially that involving lower limbs has always been regarded as a risk factor for the development of venous thromboembolism[3]. Total knee arthroplasty and total hip replacement which are widely used for patients with degenerative osteoarthritis have been proved as the most common causes for DVT in orthopedic surgeries. With the development of surgical technology, prosthesis design and chemotherapy, limb salvage and retention of function are possible for patients with a musculoskeletal tumor [3,4,5]. As the first treatment choice currently, more and more limb salvage surgeries
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