Abstract
Objectives: Comparing two different statistical models to predict female SLE patients’ outcome and analyze some related factors. Methods: 1072 female SLE patients were from the Provincial Hospital of Anhui Province and The First Ancillary Hospital of Anhui Medical University from 1990 to 2000. Two types of statistical models including loglinear and Cox proportional hazard model were performed according to this data. Results: Marriage situation, family place, admission situation, whether coming from a different division, nosocomial infection, first occurrent or not and number of drug types had significant effects on LOS after fitting of a loglinear model. Related factors from Cox proportional hazard model were little more than those selected from loglinear model. Based on the former model, a female SLE patient could be predicted that how long she would stay in hospital. But from the latter model, we could predict the ratio of the probability of improvement between different groups of female SLE patients with different individual or clinical characteristics. Conclusions: Factors affecting the length of stay of female SLE patients could be selected from either loglinear model or Cox model. But these two models would be used to do different predictions.
Highlights
Systemic lupus erythematosus (SLE) was a multisystem autoimmune disease involving both humoral and cellular aspects of the innate and acquired immune systems [1]
Because a major part of patients were treated with corticosteroids and immunosuppressive, so we focused on the different effects of single or combined type(s) of drugs treated
Based on the loglinear model, a female SLE patient could be predicted that how long she would stay in hospital
Summary
Systemic lupus erythematosus (SLE) was a multisystem autoimmune disease involving both humoral and cellular aspects of the innate and acquired immune systems [1]. It occurred worldwide and affected females more commonly than males (about 10:1). The incidence and prevalence of SLE varied among racial and ethnic groups with multisystemic manifestations of mucocutaneous, renal, neurology, serositis, etc. In the past 40 years, prognosis for patients with SLE had improved with 10-year survival approximately 90%, which partly due to these therapies [3]
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