Abstract

BackgroundCases of hemorrhagic fever with renal syndrome (HFRS) are widely distributed in eastern Asia, especially in China, Russia, and Korea. It is proved to be a difficult task to eliminate HFRS completely because of the diverse animal reservoirs and effects of global warming. Reliable forecasting is useful for the prevention and control of HFRS.MethodsTwo hybrid models, one composed of nonlinear autoregressive neural network (NARNN) and autoregressive integrated moving average (ARIMA) the other composed of generalized regression neural network (GRNN) and ARIMA were constructed to predict the incidence of HFRS in the future one year. Performances of the two hybrid models were compared with ARIMA model.ResultsThe ARIMA, ARIMA-NARNN ARIMA-GRNN model fitted and predicted the seasonal fluctuation well. Among the three models, the mean square error (MSE), mean absolute error (MAE) and mean absolute percentage error (MAPE) of ARIMA-NARNN hybrid model was the lowest both in modeling stage and forecasting stage. As for the ARIMA-GRNN hybrid model, the MSE, MAE and MAPE of modeling performance and the MSE and MAE of forecasting performance were less than the ARIMA model, but the MAPE of forecasting performance did not improve.ConclusionDeveloping and applying the ARIMA-NARNN hybrid model is an effective method to make us better understand the epidemic characteristics of HFRS and could be helpful to the prevention and control of HFRS.

Highlights

  • Hemorrhagic fever with renal syndrome (HFRS) is a rodent-borne disease caused by Hantaviruses from the family Bunyaviridae

  • One composed of nonlinear autoregressive neural network (NARNN) and autoregressive integrated moving average (ARIMA) the other composed of generalized regression neural network (GRNN) and ARIMA were constructed to predict the incidence of HFRS in the future one year

  • As for the ARIMA-GRNN hybrid model, the mean square error (MSE), mean absolute error (MAE) and mean absolute percentage error (MAPE) of modeling performance and the MSE and MAE of forecasting performance were less than the ARIMA model, but the MAPE of forecasting performance did not improve

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Summary

Introduction

Hemorrhagic fever with renal syndrome (HFRS) is a rodent-borne disease caused by Hantaviruses from the family Bunyaviridae. Cases of HFRS are widely distributed in eastern Asia, in China, Russia, and Korea. The government has adopted effective and comprehensive ways to control the transmission of HFRS [4], there are still some factors such as diverse animal reservoirs and effects of global warming will influence control effects. It is proved to be a difficult task to eliminate HFRS completely. Cases of hemorrhagic fever with renal syndrome (HFRS) are widely distributed in eastern Asia, especially in China, Russia, and Korea. It is proved to be a difficult task to eliminate HFRS completely because of the diverse animal reservoirs and effects of global warming. Reliable forecasting is useful for the prevention and control of HFRS

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