Abstract

Introduction: Tuberculosis is a communicable disease and therefore TB patient contacts are at higher risk of developing TB infection. So screening and diagnosis of latent TB is done by QFT Gold assay and Tuberculin skin test (TST). Methodology: A total of 100 TB patient contacts were taken for study, blood was drawn and processed by using the QFT G assay followed by immediate administration of TST solution in subjects forearm. Data were analyzed and results were compared. Results: QFT G assay detect LTBI with sensitivity of 88.88% and specificity of 90%. TST Sensitivity 68%, Specificity 16%. Conclusions: QFT G Assay have higher detection rate among TB contact patient. Keywords: QFT G quantiferon TB Gold, LTBI- Latent tuberculosis infection, TST – Tuberculin skin test

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