Abstract

Comparison of the Effectiveness of Intra-Articular Injections of Hyaluronic Acid and Corticosteroid in The Treatment of Patients with Knee Osteoarthritis Symptomse

Highlights

  • Osteoarthritis (OA) is a common degenerative disorder of articular cartilage accompanied by hypertrophic changes of the bone

  • The results suggested the effect of hyaluronic acid on reducing restriction of movement and corticosteroids on pain relief in patients

  • This study was performed on 34 patients who were divided into hyaluronic acid (50%) and corticosteroid (50%) groups

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Summary

Introduction

Osteoarthritis (OA) is a common degenerative disorder of articular cartilage accompanied by hypertrophic changes of the bone. The risk factors include genetics, female gender, trauma, age and obesity It is associated with progressive degeneration of cartilage and formation of new bone at the joint [1,2]. The common medicines that are administered to patients with osteoarthritis are acetaminophen, non steroidal anti-inflammatory drugs, tramadol, narcotic analgesics and corticosteroids. Other treatment alternatives such as glucosamine sulfate, chondroitin and methyl sulfonylurea methane are used for this disease [4]. Current treatments such as the use of steroids and non steroidal anti-inflammatory drugs are not satisfactory due to their significant side effects and poor therapeutic results. The aim of this study was to compare the effects of hyaluronic acid and corticosteroids in the treatment of knee osteoarthritis

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