Abstract
目的 探讨经皮椎体成形术与保守治疗骨质疏松性椎体压缩性骨折(OVCF)的临床疗效及安全性.方法 选取OVCF患者101例,按随机数字表法分为两组,手术治疗组42例,行经皮椎体成形术治疗;保守治疗组59例,采用卧休、药物等保守治疗;观察比较两组临床疗效以及安全性.结果 手术治疗组术后椎体前缘高度恢复至(37.6±6.7)mm,后凸Cobb角矫正至(5.6±3.9)°,与保守治疗组的(23.6±5.6)mm及(6.3±4.1)差异均有统计学意义(t=4.09、3.87,均P＜0.05).治疗3个月后,手术治疗组视觉模拟评分(VAS)(0.42±0.12)分,显著低于保守治疗组的(1.23±0.23)分(t=3.65、P＜0.05);手术治疗组术后3个月,Oswestry功能障碍指数问卷表(ODI)为(4.42±1.12)分,低于保守治疗组的(11.23±2.23)分(t=8.96、P＜0.05).保守治疗组出现压疮、肺部感染及泌尿系统感染共5例(5/59,8.47%),而手术治疗组则无(0/42,0.00%)(χ2=5.09、P＜0.05).结论 与保守治疗OVCF相比,经皮椎体成形术是一种简单、微创、安全有效的治疗方法。
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