Abstract
This review aimed to examine differences in outcomes with the use of intra-articular hyaluronic acid (HA) vs corticosteroids (CS) after temporomandibular joint (TMJ) arthrocentesis. Studies were searched on PubMed, Embase, Web of Science, and Google Scholar up to 15th January 2024. Randomized controlled trials (RCTs) comparing HA with CS after TMJ arthrocentesis were included. The outcomes were pain and maximal mouth opening (MMO). Ten articles corresponding to nine RCTs were included. There was no statistically significant difference in pain scores at 1 week (MD: -0.30 95% CI: -1.25, 0.65 I2=0%), 1 month (MD: -0.55 95% CI: -1.23, 0.13 I2=0%), and 6 months (MD: -0.57 95% CI: -2.10, 0.96 I2=58%) between the two groups. However, pain scores were found to be significantly lower in the HA group at 3 months (MD: -1.07 95% CI: -1.84, -0.31 I2=0%). No statistically significant difference was noted in MMO at 1 week (MD: 0.78 95% CI: -1.79, 3.35 I2=0%), 1 month (MD: 0.32 95% CI: -1.83, 2.46 I2=0%), and 3 months (MD: -0.41 95% CI: -3.90, 3.07 I2=0%) between the two groups. Descriptive analysis for studies not included in the meta-analysis also presented similar results. Low-quality evidence suggests that both intra-articular HA and CS have similar efficacy in improving pain scores and MMO after TMJ arthrocentesis.
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