Abstract
Abstract Nondialyzable and dialyzable fractions prepared from BCG culture filtrates were compared in in vitro and in vivo tests for delayed hypersensitivity. With the non-dialyzable fractions in vivo lymphocyte transformation did not correlate with in vitro inhibition of macrophage migration or skin reactivity. The degree of lymphocyte transformation was correlated with the protein content of the fractions. A carbohydrate-rich fraction did not induce lymphocyte transformation but did induce skin reactivity and inhibition of macrophage migration. Activity of the dialyzable fractions in each of the three tests was dependent on molecular size.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
