Abstract
Comparison of Effects of Halothane Anaesthesia in Horses with and Without Dexmedetomidine Continuous Rate Infusion
Highlights
The mortality rate in equine anaesthesia is much greater than in other domestic species
We found significantly lower vaporizer settings in D group for maintenance of surgical anaesthesia as well as reduction of inspired and expired halothane concentrations compared to S group with significant difference in several periods
minimal alveolar concentration (MAC) serves to estimate the potency of anaesthetic agents
Summary
The mortality rate in equine anaesthesia is much greater than in other domestic species. Johnston et al, (2004) reported 1% lethality rate in horses undergoing routine surgeries without systemic illness. In the large investigation (Johnston et al, 2002) comprising of 41 825 cases over 6 year period it was found that the death rate in colic surgeries was much greater (11.7%) than noncolic anaesthetic procedures (0.9%). The main cause for perioperative death was cardiovascular arrest or collapse (33%). The degree of hypercoagulability correlated with nonsurvival and thrombotic complications in colic horses (Prasse et al, 1993; Dukti and White, 2009; Dunkel et al, 2010; Cesarini et al, 2010). We evaluated the probability of the two anaesthetic protocols with respect to coagulation disorders
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