Comparison between colloid preload, coload, and no load in the prevention of spinal anesthesia-induced hypotension in patients undergoing inguinal hernia repair

Abstract

Background and objective The aim of this study was to know whether colloid fluid administration (either preloading or coloading) can decrease the incidence of hypotension secondary to spinal anesthesia in an elderly population undergoing inguinal hernia repair without mesh. Patients and methods After obtaining institutional ethical committee's approval and patients' informed consent, 84 patients (aged 61-89 years) scheduled for elective inguinal hernia repair were enrolled in this prospective, randomized study. We compared the incidence of hypotension and ephedrine requirement after spinal anesthesia between three groups: group P ( n = 28), in which patients were preloaded with 500 ml of 6% hydroxyethyl starch solution (130/0.4), group C ( n = 28), in which patients were coloaded with 6% hydroxyethyl starch solution during spinal anesthesia, and group N ( n = 28), in which patients were not given any fluid. Results The incidence of hypotension and the mean dose of ephedrine were not significantly different between the three groups. Conclusion We concluded that, in elderly patients undergoing inguinal hernia repair, withholding fluid loading (whether preloading or coloading) did not increase the incidence of spinal anesthesia-induced hypotension and did not affect the dose of ephedrine required to correct hypotension, if occurred.