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Abstract
ABSTRACT In this study, a comparative metabolomic investigation of Prunus salicina and Prunus domestica subsp. syriaca along with their immunological studies were carried out. In preliminary studies fruits were examined for proximate compositions (moisture, ash, fiber, fat, and protein). We found that the total phenolic content of P. domestica peel was the highest (6.11 mg/g GAE) compared to P. salicina peel (4.93 mg/g GAE). Targeted metabolomics revealed chlorogenic acid as one of the major phenolic acid in plum. Using a non-targeted metabolomics approach, metabolite discriminations among the fruit sections are represented by a Venn diagram, heatmap, and PCA. Using the METLIN database, we identified 130 metabolites in fruit sections. The cytotoxic test showed no cell damage even at higher dosages for up to 48 hours. The present study offers fresh insights into the distribution of phytochemicals in the peel and pulp sections of the fruit and can be considered for health-beneficial products and nutraceuticals.
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