Community management of asymptomatic hyperuricemic patients

Abstract

Objective To evaluate the efficacy of community management of asymptomatic hyperuricemic patients. Methods Two hundred and six patients with asymptomatic hyperuricemia in Yuetan community of Beijing were randomly and equally divided into study group and control group. Patients in study group received 12-month standardized management, while those in control group were given conventional management. After 12 months of intervention, the clinical data and related information were analyzed and the effect of intervention was evaluated by questionnaire survey. Results After 12-month intervention, the rates of unhealthy lifestyle in intervention group were significantly lower, and the exercise time was significantly more than those in control group [drinking: frequently 8.7%(9/103)vs. 11.7%(12/103), seldom 83.5% (86/103) vs. 68.9% (71/103), χ2=7.005, P=0.030; eating animal offal: seldom 88.4%(91/103) vs. 76.7%(79/103), frequently 1.9%(2/103) vs. 8.7%(9/103), χ2=6.302, P=0.043; eating seafood: seldom 74.8%(77/103) vs. 52.4%(54/103), frequently 4.8%(5/103) vs. 16.5%(17/103), χ2=12.867, P=0.002; eating thickened gravy: seldom 78.6%(81/103)vs. 53.4%(55/103), frequently 2.9%(3/103) vs. 13.6%(14/103), χ2=16.334, P=0.000; exercise time: seldom 17.5%(18/103)vs. 24.3%(25/103), 1-3 h 26.2%(27/103) vs. 38.8%(40/103), 4-6 h 32.0% (33/103) vs. 20.4%(21/103), ≥7 h 24.3%(25/103) vs. 16.5%(17/103), χ2=7.852, P=0.049]. The blood uric [(403±54) vs. (474±71) μmol/L], cholesterol [(4.6±0.8) vs.(4.9±1.0)mmol/L], triglyceride[(1.65± 0.54) vs. (1.86±0.86) mmol/L] and systolic pressure [(128±10) vs. (131±14) mmHg(1 mmHg=0.133 kPa)] in intervention group significantly lower than those in control group (t=7.984, P=0.000; t=2.803, P=0.006; t=2.130, P=0.034; t=2.059, P=0.041). The awareness rate of hyperuricemia-related knowledge in intervention group was significantly higher than that in control group [85.1% (964/1 133) vs. 45.5%(516/1 133), χ2=390.959, P=0.000]. Conclusion Standardized community management is effective for patients with asymptomatic hyperuricemia. Key words: Hyperuricemia; Disease management; Intervention studies; Questionnaires