Abstract

In the cardiomyocyte network, network size and spatial arrangement of different cellular-type are important factors for reducing the fluctuation of the beating rhythms. To study the community effect on the cell network, experimental conditions need to control the community size and to construct the network in a stepwise manner. Therefore, we tried to develop a various size of cultivation chamber using the agarose micro-chamber system combined with the multi-electrode array (MEA) measurement system (we call it On-Chip MEA system).

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