Community and domestic violence are associated with DNA methylation GrimAge acceleration and heart rate variability in adolescents

Cortical thickness, resting state heart rate, and heart rate variability in female adolescents.

Background: In obesity and/or family history of hypertension (HT) or diabetes mellitus (DM), there is a higher prevalence of cardiovascular (CV) disease in the subject, which is supposed to be due to autonomic imbalance. The alterations in cardiac autonomic functions can be assessed by heart rate variability (HRV) indicators and there is a relationship between HRV and reaction time (RT) also. Aims and Objectives: This study aims to assess the HRV and RT in adolescents with CV risk and also to find the association between these two parameters. Materials and Methods: A total of 39 adolescents with CV risk (15 females and 24 males) in the age group of 14–15 years who were obese or/and had family history of HT or DM in parents were selected. Anthropometric parameters, blood pressure, HRV parameters, and RT were recorded. Results: HRV was reduced in CV risk groups, both in females and males as compared to normal subjects and lower values were recorded in females as compared to males. There was also a negative correlation of HRV with RT both in males and females but statistically significant only in females. Conclusion: Adolescents with CV risk have reduced HRV and such individuals are more prone to CV diseases. RT, which is a marker of cognitive ability, is increased in persons with decreased HRV, and hence, such CV risk adolescents should be followed up and given timely intervention.

Physical inactivity is associated with low heart rate variability (HRV) in adolescents. However, whether the number of physical education (PE) classes impact HRV remains unclear. This cross-sectional study verified the association between the frequency of PE classes and HRV parameters in male adolescents. This study included 1152 boys (16.6 ± 1.2 years). The quantity of PE classes was assessed though questionnaire and the adolescents were stratified accordingly (no PE class; one PE class/wk; ≥2 PE classes/wk). Time- (SDNN, RMSSD, PNN50) and frequency-domains (LF, HF, sympathovagal balance) of HRV were obtained. Generalized Linear Models were used for comparing the HRV parameters according to the quantity of PE classes, adjusting for confounders. There was no difference in HRV measures of time: (SDNN, p = 0.77; RMSSD, p=0.72; PNN50, p=0.83) and frequency (LF, p=0.61; HF, p=0.61; sympathovagal balance, p=0.60) between the different frequencies of PE classes. The frequency of PE classes in not associated with HRV parameters of male adolescents.

2.56 Differences of Heart Rate Variability in First-Episode Drug-Naive Adolescents With Major Depressive Disorder

BackgroundReduced heart rate variability (HRV) suggests autonomic imbalance in the control of heart rate and is associated with unfavorable cardiometabolic outcomes. We examined whether antenatal corticosteroid (ANCS) exposure had long-term programming effects on heart rate variability (HRV) in adolescents born with very low birth weight (VLBW).MethodsFollow-up study of a cohort of VLBW 14 year-olds born between 1992 and 1996 with 50% exposed to ANCS. HRV in both the time and frequency domains using Nevrokard Software was determined from a 5 minute electrocardiogram tracing.ResultsHRV data from 89 (35 male, 53 non-black) exposed (ANCS+) and 77 (28 male, 29 non-black) unexposed (ANCS−) adolescents were analyzed. HRV did not differ between ANCS+ and ANCS− black participants. However, in non-black participants, a significant interaction between ANCS and sex was observed, with ANCS− females having significantly greater HRV than ANCS+ females and males, and ANCS− males for both time and frequency domain variables.ConclusionsAmong non-black adolescents born with VLBW, ANCS exposure is associated with reduced HRV with apparent sex-specificity. Reduced HRV has been associated with development of adverse cardiometabolic outcomes, thus supporting the need to monitor these outcomes in VLBW adolescents as they mature.

BackgroundIn adolescent Borderline Personality Disorder (BPD), interactions with caregivers often provoke dysregulation. Vagally-mediated heart rate variability (HRV), a physiological marker of regulatory capacities, shows alterations in BPD. Studies on individual and dyadic HRV in adolescents with BPD (BPD-A) and their mothers (BPD-M) are lacking. We examined 1) individual resting state -, reactivity- and recovery- HRV, 2) intrapersonal concordance of interactional quality with HRV, 3) mother-adolescent interpersonal HRV-synchrony and 4) the association of interpersonal HRV-synchrony with behavioral synchrony in a case–control design.MethodsThirty-eight (sub)syndromal BPD-A and BPD-M were compared to 35 healthy control adolescents and their mothers (HC-A/-M). HRV was assessed during a positive interaction, a stress task and resting before and after interactions (recovery). Behavior during interactions was observed and coded using the “Coding Interactive Behavior”- Manual. Data were analyzed using multilevel modeling.ResultsBPD-A showed a lower resting HRV than HC-A, while no group differences were found for mothers. From resting to positive interaction, BPD-A/BPD-M/HC-M showed a significant increase in HRV; this increase was not significant for HC-A. HRV-reactivity to stress was not significant in either group but influenced by general emotional and behavioral problems within both adolescent samples. Significant intrapersonal concordance of HRV and behavior could only be found for HC-M during the positive interaction (positive association). For BPD-M, a complete disconnect between behavior and HRV was observed. BPD-dyads and dyads lower in behavioral synchrony displayed HRV-synchrony during stress, in HC-dyads and dyads higher in behavioral synchrony during rest after dyadic interactions.ConclusionsOur study is the first investigating altered HRV-reactivity, behavior-HRV-concordance and HRV-synchrony in adolescents with BPD traits and their mothers, adding new insight to physiological regulation and co-regulation in adolescent BPD pathology. Limitations and implications of these results are discussed.

Limited data exist on the unique, additive, and interactive effects of exposure to domestic and community violence on children's functioning, particularly in community samples. This study examined relations between children's violence exposure, at home and in the community, and symptoms of externalizing and internalizing problems. Parents reported on domestic violence in the home, and children reported on community violence. Concurrent child functioning was measured through parent and teacher reports on the Child Behavior Checklist (CBCL) and child self-reports on the Children's Depression Inventory. A multi-ethnic sample of 117 children, aged 8 to 12 years, and their parents and teachers participated. Community violence was related to all measures of children's adjustment, whereas exposure to domestic violence was related only to CBCL externalizing problems. Teacher reports of child aggression were predicted by child age, community violence, and the interaction of community and domestic violence. Implications for research and clinical intervention are discussed.

Adolescent obesity is associated with impaired inhibitory control. Acute exercise can improve executive function. However, due to the influence of exercise intensity, cognitive test timing, and cardiorespiratory fitness (CF) level, the most effective exercise program remains controversial. The current study investigated the time-course effects of moderate-intensity continuous exercise (MICE) and high-intensity interval exercise (HIIE) on inhibitory control (Stroop) and task-related heart rate variability (HRV) in adolescents with different CF. A mixed experimental design of 2 CF levels (high CF, HCF; low CF, LCF) × 3 exercise methods (MICE, HIIE, CON) × 3 test timing (pre, post-0, post-20) was adopted. Heart rate variability (HRV) and Stroop task tests were conducted before exercise (pre), immediately after exercise (post-0), and 20 min after exercise (post-20). Individuals with HCF exhibited a positive decrease in Stroop response time immediately and 20 min after MICE and HIIE, compared to pretest response times (RT). Conversely, individuals with LCF showed a slight increase in Stroop task (RT) only immediately after HIIE. All individuals had a slight increase in ACC after MICE and HIIE compared to before exercise. In addition, compared with the control group, the time-domain index (the square root of the mean squared differences of successive NN intervals, RMSSD) of HRV was significantly decreased, the frequency-domain index (the absolute power of the Low-Frequency band/the absolute power of the High-Frequency band ratio, LF/HF) was significantly increased after MICE and HIIE, and the effect of HIIE on RMSSD and LF/HF was significantly greater than that of MICE. The current study found that the acute effects of MICE and HIIE on inhibitory control in obese adolescents were influenced by the interaction of cognitive test timing and cardiorespiratory fitness. Individuals with high cardiorespiratory fitness performed better on the Stroop task than individuals with low cardiorespiratory fitness. The inhibitory control of HIIE in high-cardiorespiratory obese adolescents produced positive effects similar to those in MICE but more lasting, suggesting that HIIE is more beneficial for high-cardiorespiratory obese adolescents. MICE promoted inhibitory control in obese adolescents with low cardiorespiratory fitness, but HIIE impaired inhibitory control in obese adolescents with low cardiorespiratory fitness immediately after exercise, suggesting that low cardiopulmonary fitness obese adolescents may be suitable for MICE rather than HIIE exercise intervention. The shift from balanced HRV to sympathetic dominance after acute exercise reflects increased arousal levels and may be one of the underlying mechanisms by which acute exercise brings benefits to executive function.

Objective To analyze the relation between smoking and passive smoking with heart rate variability parameters in male adolescents.Methods The sample consisted of 1,152 males, aged 14 and 19 years. Data related to smoking and passive smoking were collected using a questionnaire. RR intervals were obtained by a heart rate monitor, on supine position, for 10 minutes. After collecting the RR intervals, time (standard deviation of all RR intervals, root mean square of the squared differences between adjacent normal RR intervals and the percentage of adjacent intervals over 50ms) and frequency domains (low and high frequency and sympathovagal balance) parameters of heart rate variability were obtained.Results No significant differences between smoker and nonsmoker adolescents were observed in heart rate variability parameters (p>0.05). Similarly, heart rate variability parameters did not show significant difference between exposed and not exposed to passive smoking (p>0.05).Conclusion Cigarette smoking and passive smoking are not related to heart rate variability in adolescence.

Domestic and community violence are two pervasive societal issues. While research indicates significant connections between these forms of violence, detailed exploration of their co-occurrence and specific characteristics within intervention and prevention programs remains lacking. Understanding these complex interactions is crucial, as many programs are not designed to address the diverse manifestations of violence simultaneously. They often focus on one type, potentially overlooking the broader spectrum of violence that individuals might experience or contribute to. This study aims to illuminate the frequency and nature of these violence types within the context of intervention efforts. To bridge this gap, we engaged in a systematic, secondary analysis, delving into 1,943 conflicts documented across 25 CeaseFire program sites in Chicago between 2000 and 2015. Data included information from mediation forms regularly completed by CeaseFire staff post-mediation. Our primary focus encompassed a content analysis of these cases to establish a baseline occurrence of domestic violence within violence mediations. Subsequently, we probed the prevalence and intricate interplay between community and domestic violence, exploring potential bidirectional influences. Of the 1,943 conflicts mediated among program sites in Chicago, 151 conflicts displayed signs of interconnection with community violence, falling into the categories of retaliation or intervention. In summation, the findings underscore the entwined nature of domestic and community violence, often transitioning from one form (primarily domestic) to another (typically community-based) in the form of escalating retaliatory behaviors. Violence prevention and intervention endeavors must consider the plausible escalation patterns stemming from interconnected violence forms, significantly shaping mediation strategies.

Physical activity is a protective factor for autonomic dysfunction. However, whether this occurs in adolescents with abdominal obesity is still unclear. Thus, the aim of this study was to analyze the association between physical activity and heart rate variability (HRV) in adolescents with and without abdominal obesity. This cross-sectional study included 1152 boys (age: 17±1years). HRV measures of time (root mean square of the squared differences between adjacent normal RR intervals-RMSSD and the percentage of adjacent intervals over 50ms-PNN50) and frequency domains (balance sympathetic-vagal-LF/HF) were evaluated, as well as total physical activity, commuting physical activity, leisure-time physical activity, and abdominal obesity. All physical activity domains were associated with better RMSSD, PNN50, and LF/HF in normal weight adolescents (p<0.05), whereas in adolescents with abdominal obesity only leisure-time physical activity was associated with better PNN50 (b=0.174, p=0.035) independent of age, period of the day, body mass index, and blood pressure. In conclusion, higher leisure-time physical activity, but not total and commuting physical activity levels, was associated with improved HRV in adolescents with abdominal obesity.

Immediate and sustained effects of intermittent exercise on inhibitory control and task-related heart rate variability in adolescents

Sleep Quality and Heart Rate Variability in Adolescents with Type 1 or Type 2 Diabetes

Sleep quality and heart rate variability in adolescents with type 1 or type 2 diabetes.

The negative impacts of community or domestic violence on individuals self-rated health are known, but there is little evidence of the combined effect of these two types of interpersonal violence.To...