Abstract
Commentary: Efficacy and Safety of Dupilumab in Moderate-to-Severe Bullous Pemphigoid.
Highlights
Bullous pemphigoid (BP), a chronic autoimmune cutaneous blistering disorder affecting predominantly the elderly, is characterized by skin tense bullae formation and pruritus symptoms [1]
Given the significant adverse effect caused by systemic steroids, novel targeted therapeutic approaches are warranted to provide corticosteroid-sparing with a favorable safety profile and induce durable drug responses
Traditional Chinese medicine, Tripterygium wilfordii Hook F (TwHF), in the treatment of BP is widespread in China on its immunomodulatory and anti-inflammatory properties
Summary
Bullous pemphigoid (BP), a chronic autoimmune cutaneous blistering disorder affecting predominantly the elderly, is characterized by skin tense bullae formation and pruritus symptoms [1]. A Commentary on Efficacy and Safety of Dupilumab in Moderate-to-Severe Bullous Pemphigoid By Zhang Y, Xu Q, Chen L, Chen J, Zhang J, Zou Y, Gong T and Ji C (2021). Given the significant adverse effect caused by systemic steroids, novel targeted therapeutic approaches are warranted to provide corticosteroid-sparing with a favorable safety profile and induce durable drug responses.
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