Abstract
A novel method for measuring the optical properties of highly absorbing and scattering biological media is described. The method combines frequency-domain photothermal radiometry (FD-PTR) with spatially resolved diffuse reflectance (SR-DR) techniques aimed at improving sensitivity on the determination of both scattering and absorption coefficients. Simulation results with Monte-Carlo and Diffusion Theory approaches that assess the scope and feasibility of the method are presented. An optical fiber probe for SR-DR measurements was constructed for operations at small source-detector separations and an FD-PTR system was adapted for quasi-simultaneous operation with the probe. Several experiments on epoxy phantoms that illustrate the validity and potential of the method are presented.
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