Abstract
1. 1. Lysergic acid diethylamide (LSD) evokes distal retinal pigment light adaptation and erythrophoric pigment concentration. 2. 2. The erythrophoric responses to LSD are not dependent on the amount of light striking the rhabdoms in the eyes. 3. 3. Isolysergic acid amide and psilocin evoke erythrophoric pigment concentration in intact fiddler crabs but not in eyestalkless crabs nor in vitro in isolated legs. It was already known that LSD evokes such pigment concentration in intact crabs only. 4. 4. Of the three alkaloids used, LSD was the most potent while psilocin was the least potent in evoking the observed effects on the erythrophores. 5. 5. These indole alkaloids do not stimulate the erythrophores directly. Their actions appear to be mediated by the neuroendocrine system.
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