Abstract

Diverticular disease is a common condition affecting large intestine in the western world, which, although remains asymptomatic in majority of people, can present with abdominal pain, acute diverticulitis, perforation, haemorrhage, intestinal obstruction and fistulation through neighbouring organs. Complicated colonic diverticular disease (CDD) is associated with significant morbidity and mortality. Increasing urbanisation globally with intake of diet deficient in fibres has led to CDD as a significant problem; hence awareness of CDD is paramount for its prevention and appropriate management. The purpose of this article is to provide a comprehensive review of the epidemiology, pathophysiology, clinical presentations, and current management of diverticular disease of the colon and its complications.

Highlights

  • Colonic diverticular disease (CDD) is an acquired condition marked by mucosal herniation through defects in the colonic wall, termed both as a "disease of the 20th century" and a "disease of Western civilization", remains asymptomatic in majority of cases, should be entertained in the differential diagnosis of all patients presenting with abdominal pain.[1]

  • The management of the CDD through a multidisciplinary team consisting of surgeons, physicians, radiologists, dieticians and stoma therapists leads to best outcomes.[2]

  • With the increasing urbanisation in the developing world such as Nepal, the emergence of cases of CDD must be borne in mind while dealing with patients with abdominal pain

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Summary

Introduction

Colonic diverticular disease (CDD) is an acquired condition marked by mucosal herniation through defects in the colonic wall, termed both as a "disease of the 20th century" and a "disease of Western civilization", remains asymptomatic in majority of cases, should be entertained in the differential diagnosis of all patients presenting with abdominal pain.[1] Complications of CDD, can cause significant morbidity and mortality, leading to a significant financial impact on health care systems. The management of the CDD through a multidisciplinary team consisting of surgeons, physicians, radiologists, dieticians and stoma therapists leads to best outcomes.[2] This article provides an up to date review on the aetiopathogenesis and management of CDD with special emphasis on the controversies surrounding the management of its complications. There is no gender variation.[4]

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