Abstract
A 78-year-old woman was diagnosed with a proximal gastric adenocarcinoma and underwent an elective D2 total gastrectomy with splenectomy. Subsequent histopathology revealed the presence of another tumour at the gastric antrum. This was a small benign gastrointestinal stromal tumour (GIST) mixed with gastric adenocarcinoma cells similar to those of the main gastric tumour i.e. a collision tumour. The literature has only few previous reports of this very rare association. It is not known whether this synchronicity is incidental or there is a causative factor inducing the development of tumours of different histotypes in the same organ. Pathologists, oncologists and surgeons should be aware of this interesting condition.
Highlights
Adenocarcinoma is the most common histological type of gastric tumour. It may coexist with another synchronous tumour of different histological type in a different part of the stomach
We present here the very rare combination of a synchronous proximal gastric adenocarcinoma and a distal gastric collision tumour consisting of gastrointestinal stromal tumour (GIST) and adenocarcinoma cells similar to those of the main gastric tumour
There are only a few previous reports of simultaneous adenocarcinoma and GIST in the stomach [1,2,3]. In these cases the synchronous tumours were located in different parts of the stomach
Summary
Adenocarcinoma is the most common histological type of gastric tumour. It may coexist with another synchronous tumour of different histological type in a different part of the stomach. Gastric adenocarcinoma may coexist most commonly with lymphoma and less commonly with carcinoid and gastrointestinal stromal tumour (GIST). Cells of different histological types may intermix and form a collision tumour in the stomach.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
