Abstract
BackgroundTo evaluate the prognosis of acute cerebral infarction at 1-year follow-up in different circulation infarctions.MethodsClinical data of 858 consecutive patients with acute cerebral infarction were collected. Of the 858 cases, 21 (2.45%) were lost to follow-up and 837 completed follow-up and thus were enrolled in this study. At 1-year follow-up, death or moderate-to-severe dysfunction (modified Rankin Scale (mRS) ≥ 3 points) was regarded as the poor prognostic endpoint. Univariate analysis and multivariate logistic stepwise regression analysis were performed to assess the prognosis. The prediction probability of indicators was obtained for the multivariate model, and the receiver operating characteristic curve was delineated to calculate the area under the curve (AUC) to predict the fitness of the model.ResultsThe older the age, the greater the probability of a poor prognosis. Patients with previous diabetes and cerebral infarction had a poor prognosis. The higher the National Institutes of Health Stroke Scale and mRS scores and the lower the Barthel index at admission, the worse the prognosis of the patients. The longer the hospital stay, the worse the prognosis of the patients. The prognosis of different circulation infarctions was different. The AUC of the multivariate model was AUC = 0.893, and the 95% confidence interval was 0.870–0.913, indicating a good fit. The prognosis of anterior circulation infarction (ACI) was worse than that of posterior circulation infarction (PCI) (P < 0.05). The prognosis of patients with ACI and PCI was not significantly different from that of patients with ACI or PCI alone (P > 0.05).ConclusionsDiabetes, the Barthel index at admission and previous cerebral infarction are poor prognostic factors of acute cerebral infarction. The prognosis of ACI is worse than that of PCI. Different factors affect the prognosis of different circulatory system infarctions.
Highlights
To evaluate the prognosis of acute cerebral infarction at 1-year follow-up in different circulation infarctions
Age, consciousness level, hyperglycaemia and stroke mechanisms are related to the prognosis after acute cerebral infarction, which may differ between anterior circulation infarction (ACI) and posterior circulation infarction (PCI) [5, 6]
Data were consecutively collected on 858 patients with acute cerebral infarction who were hospitalised in the Department of Neurology, Aerospace Center Hospital, Peking University Aerospace School of Clinical Medicine from December 1, 2012 to November 4, 2015
Summary
To evaluate the prognosis of acute cerebral infarction at 1-year follow-up in different circulation infarctions. Acute cerebral infarction accounts for approximately 85% of all strokes and has a high disability and mortality rate [1, 2]. Few clinical studies compared the aetiology and prognostic factors of different circulation strokes, and variable analyses are unavailable [3, 4]. Age, consciousness level, hyperglycaemia and stroke mechanisms are related to the prognosis after acute cerebral infarction, which may differ between anterior circulation infarction (ACI) and posterior circulation infarction (PCI) [5, 6]. Chen et al BMC Cardiovasc Disord (2021) 21:521 prognostic factors of acute cerebral infarction at 1-year follow-up in different circulation infarctions
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