Cognitive functions in patients in the long-term period of microsurgical treatment of cerebral aneurysms

Abstract

Objective: to study cognitive functions in patients in the long-term period of microsurgical treatment of cerebral aneurysms. Materials methods: on the basis of the University Clinic of the Moscow State Medical University. A.I. Evdokimov and the Department of Emergency Neurosurgery of the N.V. Sklifosovsky Research Institute for Emergency Medicine, an analysis of cognitive functions was carried out in 212 patients operated on by a microsurgical method since 2013. Results: in the long-term period of surgical treatment of cerebral aneurysms, cognitive impairments of varying severity were detected in 78 patients (37 %). The main factors negatively affecting cognitive functions were the severity of the patient’s condition before surgery, corresponding to Hunt-Kosnik III–V, the age of patients over 60 years old, body mass index over 30, localization of the aneurysm in the basin of the anterior cerebral artery and vertebrobasilar basin, patients’ condition discharge according to the Glasgow Grade IV–III Outcome Scale. No significant dependence of cognitive impairment on the severity of subarachnoid hemorrhage and the gender of patients was found. On the contrary, the severity of anxiety and depression, which was assessed on the HADS scale, was twice as likely to be observed in female patients as compared with male patients. Conclusion: it is obvious that the persistence of cognitive deficit and mental disorders, in the form of anxiety and depression, in the long-term period of surgical treatment of cerebral aneurysms dictates the need for long-term dispensary observation and correction of the revealed disorders.