Abstract
Objective: Pancytopenia is a clinicohematological problem with wide spread discriminated diagnosis. A through evaluation of patient is necessary to identify the cause as large number of patients has reversible etiology and early diagnosis may be lifesaving. Diagnosis of pancytopenia requires microscopic examination of bone marrow aspirates to assess the overall cellularity and morphology. This study was conducted with the aim to find out the cause of pancytopenia on the basis of bone marrow findings. Methods: The present study was conducted in the department of pathology over a period of one year. A total of 169 patients were included in the study that fulfilled the criteria of pancytopenia. A detailed clinical history and physical examination followed by complete blood count, peripheral smear examination and bone marrow aspiration was done in all cases. Results: There was slight male predominance with male to female ratio of 1.2:1. The majority of patients were in second and third decade. The main cause of pancytopenia was megaloblastic anemia followed by mixed nutritional deficiency anemia and others. Conclusion: This study emphasized that in developing countries like India majority of the patients had reversible etiology and patients can be put on a trial of hematinics and close haematological follow up. Key words: Pancytopenia, bone marrow, megaloblastic anemia, aplastic anemia
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