Abstract
Meeting Abstracts1 May 1973Clinical Value of A New Antibiotic Assay.Larry W. Rumans, M.D., Douglas W. Voth, M.D., Sharon P. Wagoner, Chien Liu, M.D., F.A.C.P.Larry W. Rumans, M.D.Search for more papers by this author, Douglas W. Voth, M.D.Search for more papers by this author, Sharon P. WagonerSearch for more papers by this author, Chien Liu, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-78-5-826_5 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptMeasurement of serum concentrations of potentially toxic antibiotics, especially in patients with compromised renal function, is desirable for optimal therapy. The applicability of nomograms based on renal function for estimating drug dosage has been emphasized by others; by comparing predicted with observed drug concentrations the usefulness of the nomograms can be tested. A 4-hour microassay, based on a well-diffusion method, was developed for the quantitative determination of aminoglycoside drugs, for example, gentamicin. Wells (5 mm) were cut in trypticase soy agar plates (100 mm x 15 mm), which were preseeded withBacillus globigii. Thirty-picolitre serum samples were distributed in the... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Kansas City, Kansas. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 May 1973Volume 78, Issue 5Page: 826-827KeywordsAntibioticsAttentionBacillusDrugs Issue Published: 1 May 1973 PDF downloadLoading ...
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