Abstract
Laterally spreading tumors (LSTs) are increasingly encountered with the uptake of colorectal cancer screening programs. The approach to LSTs is determined by the risk of submucosal invasive cancer (SMIC), because this dictates the most appropriate endoscopic or surgical intervention. In the West, endoscopic mucosal resection (EMR) is the first-line treatment for LSTs without SMIC, given its cost-effectiveness, superior safety profile, and patient quality of life when compared with surgery. Conversely, LSTs with SMIC have been traditionally referred for surgery.
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