Abstract

目的 分析30例HELLP综合征的临床表现及母儿结局,探讨该病目前的诊治和预后. 方法对30例HELLP综合征进行回顾性分析,其中完全性HELLP 19例,部分性HELLP 11例,比较两组的实验室指标、临床表现、母儿并发症和分娩结局. 结果完全性HELLP组的乳酸脱氢酶值为(622±481)U/L,显著高于部分性组(369±101)U/L(P 0.05).完全性HELLP组的分娩孕周为(32±4)周,新生儿体重(1617±603) g;部分性组的分娩孕周为(36±3)周,新生儿体重(2381±786) g,两组比较差异有显著性(P均 0.05).产后HELLP综合征者2例,均为完全性.两组患者的血小板和肝功能均于产后24 h开始恢复,产后72 h血小板恢复正常,产后第5天肝功能恢复正常. 结论完全性HELLP综合征的临床病情较部分性更加严重.但如能及时诊治,二者的预后(包括实验室指标的恢复和围产儿死亡率)无显著差别。

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