Abstract

Objective To evaluate the clinical significance of detecting cardiac muscle zymogram in the neonatal asphyxia patients with myocardial danlage.Method 86 cases of neonates with asphyxia were divided into mil dand severe groups.Another 52 cases of normal newbons were as control group.The activity of AST,CK,CK-MB,LDH were measured.Results Differences of cardiac muscle zymogram among the three groups were statistical significance(P<0.01),and cardiac muscle zymogram changes before and after treatment in children with severe asphyxia were statistical significance(P<0.05).Conclusion Cardiac muscle zymogram detection has important clinical significance to determine the severity of neollatal asphyxia and the therapeutic effects.It can help early diagnosis of neonatal asphyxia whether with myocardial damage and is of important clinical significance to determine the patient 抯 condition,treatment effect and prognosis. Key words: Cardiac muscle zymogram; Newborn infant; Asphyxia; Cardiac damage

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